Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 1.00 |
| ▸ | CES1 | P23141 | 7/20 | 1.00 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163462 | 1.00 | FAAH (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL4835098 | 1.00 | FAAH (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL4840954 | 0.85 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL4840946 | 0.85 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL14196696 | 0.85 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL3193600 | 0.83 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL3193554 | 0.80 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL3193561 | 0.80 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL4836309 | 0.80 | CES1 (1.00) | FAAHCES1NCEH1 | |
| SCHEMBL4831663 | 0.80 | CES1 (1.00) | FAAHCES1NCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | claimed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | claimed |
| EP-1812427-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2007-08-01 | — | — | EP | claimed |
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-11 | — | — | US | claimed |
| WO-2006044617-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-04-27 | — | — | WO | claimed |
| US-20110183947-A1 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |
| WO-2010005572-A2 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-24 | — | — | US | disclosed |
| US-7351724-B2 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1812427-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2007-08-01 | — | — | EP | disclosed |
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-11 | — | — | US | disclosed |
| WO-2006044617-A1 | OXADIAZOLE KETONE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100212-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 60/4885NCEH1 22/4885 |
| US-20110183947-A1 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS | FAAH, FAAH2, FADS1 | FAAH 1/4885CES1 11/4885NCEH1 17/4885 |
| US-20080096931-A1 | Oxadiazole ketone inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 60/4885NCEH1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.