Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15811229 | 0.86 | CYP1A1 (0.39) | ALOX5JAK2DHFRMAP4K4IMPDH2 | |
| SCHEMBL1615585 | 0.86 | ALDH1A1 (0.53) | ALOX5ALDH1A1JAK2DHFRMAP4K4 | |
| SCHEMBL14479463 | 0.84 | ALDH1A1 (0.50) | ALOX5ALDH1A1JAK2DHFRMAP4K4 | |
| SCHEMBL1614546 | 0.84 | ALDH1A1 (0.50) | ALOX5ALDH1A1JAK2DHFRMAP4K4 | |
| SCHEMBL29484416 | 0.83 | METAP2 (0.39) | MAOAESR2ESR1MEN1KMT2A | |
| SCHEMBL17025411 | 0.83 | METAP2 (0.39) | MAOAESR2ESR1MEN1KMT2A | |
| SCHEMBL19336421 | 0.81 | HPRT1 (0.41) | ALDH1A1HSD17B10HPGDCYP1A2TDP1 | |
| SCHEMBL29617337 | 0.81 | HPRT1 (0.41) | ALDH1A1HSD17B10HPGDCYP1A2TDP1 | |
| SCHEMBL12741708 | 0.81 | HPRT1 (0.41) | ALDH1A1HSD17B10HPGDCYP1A2TDP1 | |
| SCHEMBL23722415 | 0.80 | LIMK1 (0.44) | ALOX5ALDH1A1JAK2MAP4K4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-01-23 | — | — | WO | disclosed |