SCHEMBL1614546

SCHEMBL1614546

c1ccc(-c2ccc3c4ccccc4c4ccc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
ALOX5 P09917 1/20 0.48
JAK2 O60674 2/20 0.45
MAOA P21397 1/20 0.44
DHFR P00374 1/20 0.44
MAP4K4 O95819 1/20 0.44
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ESR2 Q92731 3/20 0.43
MEN1 O00255 3/20 0.43
MAPT P10636 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14479463 1.00 ALDH1A1 (0.50) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL1615585 0.97 ALDH1A1 (0.53) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL20431790 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL22173462 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL25668832 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL23432303 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL25669185 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL14958604 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL20431772 0.95 ALDH1A1 (0.45) ALDH1A1ALOX5JAK2MAOADHFR
SCHEMBL19878962 0.95 MEN1 (0.48) ALDH1A1ALOX5JAK2MAOADHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12082493-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-09-03 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-10957858-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-08 US disclosed
US-10312450-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-06-04 US disclosed
EP-3424918-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-3112336-B1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-08-01 EP disclosed
US-20170179394-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2017-06-22 US disclosed
EP-3112336-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2017-01-04 EP disclosed
EP-2511254-B1 Single triphenylene chromophores in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORP (US) 2016-05-11 EP disclosed
US-20150001524-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-01-01 US disclosed
US-20140103327-A1 HOST MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-04-17 US disclosed
US-8652652-B2 Single triphenylene chromophores in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US disclosed
EP-2200956-B1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2013-07-03 EP disclosed
EP-2511254-A2 Single triphenylene chromophores in phosphorescent light emitting diodes Universal Display Corporation (US) 2012-10-17 EP disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
EP-2200956-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-06-30 EP disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12082493-B2 Organic electroluminescent materials and devices NONO, ORC3, TYR ALDH1A1 668/4885ALOX5 3242/4885JAK2 3510/4885
US-20170179394-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 ALDH1A1 320/4885ALOX5 3202/4885JAK2 3203/4885
US-10312450-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ALDH1A1 320/4885ALOX5 3202/4885JAK2 3203/4885
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES TYR, PNP, MAPRE2 ALDH1A1 1731/4885ALOX5 3813/4885JAK2 3251/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR ALDH1A1 668/4885ALOX5 3242/4885JAK2 3510/4885
US-10957858-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ALDH1A1 320/4885ALOX5 3202/4885JAK2 3203/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ALDH1A1 320/4885ALOX5 3202/4885JAK2 3203/4885
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 ALDH1A1 320/4885ALOX5 3202/4885JAK2 3203/4885
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 ALDH1A1 320/4885ALOX5 3202/4885JAK2 3203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.