Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748752 | 0.71 | CYP19A1 (0.56) | ACHEMETAP1CYP19A1 | |
| SCHEMBL21408186 | 0.69 | IDO1 (0.57) | HTR2AIDO1MAPT | |
| SCHEMBL5951221 | 0.68 | ACHE (0.42) | ACHEMETAP1IDO1CYP19A1 | |
| SCHEMBL5505282 | 0.68 | IDO1 (0.48) | IDO1CYP19A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2345374 | 0.66 | ACHE (0.55) | ACHEMETAP1CYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL30785363 | 0.66 | ACHE (0.55) | ACHEMETAP1CYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL5951222 | 0.65 | IDO1 (0.48) | IDO1CYP19A1MAPTSMN1; SMN2 | |
| SCHEMBL5951963 | 0.64 | ACHE (0.41) | ACHEHTR2AMETAP1CYP19A1MAPT | |
| SCHEMBL15874768 | 0.64 | CYP19A1 (0.52) | ACHEIDO1CYP19A1KDM4EMAPT | |
| SCHEMBL15874769 | 0.64 | CYP19A1 (0.52) | ACHEIDO1CYP19A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-01-23 | — | — | WO | disclosed |