Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21636144 | 0.85 | MGLL (0.65) | MGLL | |
| SCHEMBL20397304 | 0.82 | MGLL (0.64) | MGLL | |
| SCHEMBL18418309 | 0.82 | MGLL (0.46) | MGLL | |
| SCHEMBL20411495 | 0.81 | MGLL (1.00) | MGLL | |
| SCHEMBL20411496 | 0.81 | MGLL (1.00) | MGLL | |
| SCHEMBL21625003 | 0.80 | MGLL (0.46) | MGLL | |
| SCHEMBL18422338 | 0.80 | MGLL (0.46) | MGLL | |
| SCHEMBL18422794 | 0.78 | MGLL (0.44) | MGLL | |
| SCHEMBL20397335 | 0.78 | MGLL (1.00) | MGLL | |
| SCHEMBL18422661 | 0.77 | MGLL (0.49) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309669-A1 | Heterocyclic Spiro Compounds As MAGL Inhibitors | PFIZER INC. (US) | 2021-10-07 | — | — | US | disclosed |
| US-20210309669-A1 | Heterocyclic Spiro Compounds As MAGL Inhibitors | PFIZER INC. (US) | 2021-10-07 | — | — | US | disclosed |
| WO-2020016710-A1 | HETEROCYCLIC SPIRO COMPOUNDS AS MAGL INHIBITORS | PFIZER INC. (US) | 2020-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309669-A1 | Heterocyclic Spiro Compounds As MAGL Inhibitors | MAG, ECH1, ECHS1 | MGLL 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.