SCHEMBL21636320

SCHEMBL21636320

N#Cc1cccc(-c2cc(-c3ccccc3)nc(I)n2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.54
GABRG2 P18507 1/20 0.54
GABRB3 P28472 1/20 0.54
GABRA5 P31644 1/20 0.54
GABRA3 P34903 1/20 0.54
ALDH1A3 P47895 1/20 0.51
XDH P47989 1/20 0.50
CTSS P25774 1/20 0.49
CTSK P43235 1/20 0.49
ADORA2A P29274 4/20 0.49
ADORA1 P30542 3/20 0.49
IDO1 P14902 2/20 0.49
GRM5 P41594 1/20 0.48
CLK4 Q9HAZ1 4/20 0.47
ADORA2B P29275 2/20 0.46
MAOB P27338 1/20 0.46
ATR Q13535 1/20 0.45
ALDH1A1 P00352 3/20 0.45
CYP1A2 P05177 3/20 0.45
CYP2C19 P33261 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663608 0.87 GABRA1 (0.56) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL31663506 0.85 CLK4 (0.61) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL20933285 0.84 GABRA1 (0.57) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15308290 0.84 L3MBTL1 (0.65) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL10431256 0.83 GABRA1 (0.59) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL23384028 0.83 MEN1 (0.56) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL26220465 0.83 GABRA1 (0.52) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL26275522 0.83 GABRA1 (0.56) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL25930258 0.82 GABRA1 (0.59) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL31273466 0.81 GABRG2 (0.67) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020016233-A1 COMPOUND AND ORGANIC SEMICONDUCTING LAYER, ORGANIC ELECTRONIC DEVICE, DISPLAY DEVICE AND LIGHTING DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2020-01-23 WO disclosed