Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.46 |
| ▸ | ADA | P00813 | 1/20 | 0.46 |
| ▸ | PI4KA | P42356 | 4/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548595 | 0.87 | ADA (0.56) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL22990449 | 0.86 | P2RY1 (0.54) | PI4K2AADAP2RY1ADORA1POLB | |
| SCHEMBL20324651 | 0.83 | TAS1R3 (0.47) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL24695057 | 0.76 | ADA (0.54) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL9153371 | 0.76 | ADA (0.51) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL9153368 | 0.76 | ADA (0.51) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL12060727 | 0.76 | ADA (0.51) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL13488853 | 0.75 | BCHE (0.53) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL22352154 | 0.75 | BCHE (0.53) | PI4K2AADAPI4KAPI4K2BPI4KB | |
| SCHEMBL12149869 | 0.75 | BCHE (0.53) | PI4K2AADAPI4KAPI4K2BPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016782-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH, INC. (US) | 2020-01-23 | — | — | WO | disclosed |