Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.51 |
| ▸ | PI4KA | P42356 | 5/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153368 | 1.00 | ADA (0.51) | ADAPI4K2API4KAPI4K2BPI4KB | |
| SCHEMBL12060727 | 1.00 | ADA (0.51) | ADAPI4K2API4KAPI4K2BPI4KB | |
| SCHEMBL10438061 | 0.88 | PI4K2A (0.38) | ADAPI4K2API4KAPI4K2BPI4KB | |
| SCHEMBL9152204 | 0.88 | PI4K2A (0.38) | ADAPI4K2API4KAPI4K2BPI4KB | |
| SCHEMBL9149291 | 0.86 | AHCY (0.45) | TP53ADORA2AADORA3ADORA2BAHCY | |
| SCHEMBL9149297 | 0.86 | AHCY (0.45) | TP53ADORA2AADORA3ADORA2BAHCY | |
| SCHEMBL24695057 | 0.83 | ADA (0.54) | ADAPI4K2API4KAPI4K2BPI4KB | |
| SCHEMBL9548595 | 0.83 | ADA (0.56) | ADAPI4K2API4KAPI4K2BPI4KB | |
| SCHEMBL9152200 | 0.81 | ALDH1A1 (0.56) | MAPK1ALDH1A1ADORA3 | |
| SCHEMBL12188777 | 0.80 | PI4K2A (0.51) | PI4K2API4KAPI4K2BPI4KBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449664-A | Nucleosides | SYNTEX (U.S.A.) INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0457326-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0371366-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1990-06-06 | — | — | EP | disclosed |