SCHEMBL216382

SCHEMBL216382

CCCC(C)C.N=C=O.N=C=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
TRPM8 Q7Z2W7 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
FDPS P14324 1/20 0.31
CA1 P00915 1/20 0.31
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3125185 1.00
SCHEMBL7525622 0.84 CA1 (0.35) TRPM8CA1
SCHEMBL4810926 0.83 LMNA (0.38) TSHRTRPM8FDPSCA1
SCHEMBL27576249 0.83 LMNA (0.38) TSHRTRPM8FDPSCA1
SCHEMBL28841264 0.82 TSHR (0.46) TSHRCHRM1AKR1A1CHRM3HTR2A
SCHEMBL11344550 0.81 OPRM1 (0.44) TRPM8FDPSCA1
Methane SCHEMBL29039910 0.81 LMNA (0.36) TSHRTRPM8FDPSCA1
SCHEMBL215973 0.81 OPRM1 (0.44) TRPM8FDPSCA1
SCHEMBL2487739 0.80
SCHEMBL4635 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114423736-B Method for distilling isocyanates 科思创德国股份有限公司 2025-02-18 CN claimed
US-20250019483-A1 PREPARATION OF POLYISOCYANATES CONTAINING IMINOOXADIAZINEDIONE GROUPS AND THEIR USE BASF SE (DE) 2025-01-16 US claimed
EP-4433519-A1 PREPARATION OF POLYISOCYANATES CONTAINING IMINOOXADIAZINEDIONE GROUPS AND THEIR USE BASF SE (DE) 2024-09-25 EP claimed
CN-118290461-A Isocyanate polymerization catalyst and preparation method thereof, and preparation method of polyisocyanate 万华化学集团股份有限公司 2024-07-05 CN claimed
CN-118287135-A Isocyanate polymerization catalyst and preparation method thereof, polyisocyanate composition and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN claimed
WO-2024140237-A1 SOLID-STATE BATTERY CELL, AND PREPARATION METHOD AND USE 北京卫蓝新能源科技有限公司 2024-07-04 WO claimed
CN-117996204-A Manufacturing method of in-situ curing electrolyte battery and battery 北京卫蓝新能源科技有限公司 2024-05-07 CN claimed
EP-3481885-B1 HIGH-SOLIDS CONTENT SOLVENT-BASED ADHESIVE COMPOSITIONS AND METHODS OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-09-13 EP claimed
US-11746265-B2 Two-component adhesive compositions and methods of making same THE DOW CHEMICAL COMPANY (US) 2023-09-05 US claimed
WO-2023138938-A1 PREPARATION OF POLYISOCYANATES CONTAINING IMINOOXADIAZINEDIONE GROUPS AND THEIR USE BASF SE (DE) 2023-07-27 WO claimed
US-20030153713-A1 Low-temperature-curable, solid polyurethane powder coating compositions containing uretdione groups DEGUSSA AG (DE) 2003-08-14 US claimed
US-6491986-B2 PROTECTIVE COATINGS DEGUSSA AG (DE) 2002-12-10 US claimed
US-20020120089-A1 Catalyst and process for preparing low-viscosity and color-reduced polyisocyanates containing isocyanurate groups DEGUSSA AG (DE) 2002-08-29 US claimed
US-20010024696-A1 Transparent or pigmented powder coating materials with crosslinkers comprising hydroxyalkylamides and polyisocyanates containing uretdione groups DEGUSSA-HULS AKTIENGESELLSCHAFT (DE) 2001-09-27 US claimed
EP-0934963-B1 Aqueous polyurethane dispersions based on 2-methylpentane-1,5-diisocyanate DEGUSSA (DE) 2001-08-22 EP claimed
EP-0610068-B1 Emulsifying epoxy resin composition and curable composition ASAHI DENKA KOGYO KK (JP) 1999-10-27 EP claimed
US-5837795-A Solvent-free heat-curing one-component coating materials HUELS AKTIENGESELLSCHAFT (DE) 1998-11-17 US claimed
US-5391596-A Polyetherurethane copolymers ASAHI DENKA KOGYO K.K. (JP) 1995-02-21 US claimed
EP-0610068-A2 Emulsifying epoxy resin composition and curable composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-08-10 EP claimed
US-5215847-A Process for obtaining improved dispersion of components in toner particles XEROX CORPORATION (US) 1993-06-01 US claimed