SCHEMBL21639941

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7691375	0.90	OPRL1 (0.60)	OPRL1OPRM1OPRD1OPRK1ALDH1A1
	SCHEMBL13597038	0.85	OPRL1 (1.00)	OPRL1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL69083	0.83	OPRM1 (0.56)	OPRL1OPRM1OPRD1OPRK1NPSR1
	SCHEMBL1489316	0.82	OPRM1 (0.50)	OPRL1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL21590633	0.79	OPRM1 (0.49)	OPRL1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL18785421	0.77	OPRM1 (0.49)	OPRL1OPRM1OPRD1OPRK1ALDH1A1
	SCHEMBL2142315	0.77	OPRM1 (0.51)	OPRL1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL13317173	0.77	OPRM1 (0.51)	OPRL1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL30150919	0.77	OPRM1 (0.52)	OPRL1OPRM1OPRD1OPRK1KMT2A
	SCHEMBL21133658	0.76	NPSR1 (0.51)	OPRL1OPRM1OPRD1OPRK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.