SCHEMBL21643041

SCHEMBL21643041

Cn1cc(CC(N)C(=O)O)c(C#N)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 6/20 0.40
GRIA1 P42261 5/20 0.40
GRIA2 P42262 5/20 0.40
GRIA3 P42263 5/20 0.40
NOS3 P29474 2/20 0.40
NOS1 P29475 2/20 0.40
NOS2 P35228 2/20 0.40
USP2 O75604 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
RECQL P46063 2/20 0.40
PKM P14618 2/20 0.40
RGS12 O14924 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
NFKB1 P19838 1/20 0.40
CASP1 P29466 1/20 0.40
BRCA1 P38398 1/20 0.40
THPO P40225 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21643040 1.00 GRIA4 (0.40) GRIA4GRIA1GRIA2GRIA3NOS3
SCHEMBL21639112 0.73 CTSS (0.46)
SCHEMBL21639110 0.73 CTSS (0.46)
SCHEMBL8785433 0.72 ALDH1A1 (0.38) ALDH1A1KDM4EKMT2ANPSR1TDP1
SCHEMBL21643059 0.68 SLC7A5 (0.44) GRIA2NOS3NOS1NOS2USP2
SCHEMBL21643058 0.68 SLC7A5 (0.44) GRIA2NOS3NOS1NOS2USP2
SCHEMBL25353489 0.65 GRIA1 (0.49) GRIA4GRIA1GRIA2GRIA3NOS3
SCHEMBL21879115 0.65 GRIA1 (0.49) GRIA4GRIA1GRIA2GRIA3NOS3
SCHEMBL21946640 0.65 GRIA1 (0.49) GRIA4GRIA1GRIA2GRIA3NOS3
SCHEMBL10059980 0.65 GRIA4 (0.54) GRIA4GRIA1GRIA2GRIA3PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 US disclosed
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORPORATION (JP) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND VIP, NPPA, NGLY1 GRIA4 3350/4885GRIA1 2562/4885GRIA2 3146/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 GRIA4 3350/4885GRIA1 2562/4885GRIA2 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.