Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20509680 | 0.93 | GRM4 (0.41) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL29184295 | 0.90 | MAOB (0.44) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL30779587 | 0.85 | CFTR (0.46) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL21644521 | 0.85 | CFTR (0.46) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL29184302 | 0.81 | GRM4 (0.40) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL30779665 | 0.80 | NOTUM (0.49) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL1868235 | 0.80 | NOTUM (0.49) | MAOBMAOAMEN1KMT2ALRRK2 | |
| SCHEMBL21678064 | 0.80 | TRPV3 (0.39) | KMT2ASGMS2MAPT | |
| SCHEMBL30779582 | 0.78 | SGMS2 (0.62) | MEN1KMT2ALRRK2GAASGMS2 | |
| SCHEMBL21644687 | 0.78 | SGMS2 (0.62) | MEN1KMT2ALRRK2GAASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479528-B2 | Heat shock protein 90 inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-10-25 | — | — | US | disclosed |
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | MAOB 3544/4885MAOA 3100/4885MEN1 4724/4885 |
| US-11479528-B2 | Heat shock protein 90 inhibitors | HSP90AB1, HSP90AB2P, HSP90AA1 | MAOB 3544/4885MAOA 3100/4885MEN1 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.