Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644521 | 1.00 | CFTR (0.46) | CFTRMAOBMEN1KMT2AMAOA | |
| SCHEMBL1868235 | 0.93 | NOTUM (0.49) | MAOBMEN1KMT2AMAOALRRK2 | |
| SCHEMBL30779665 | 0.93 | NOTUM (0.49) | MAOBMEN1KMT2AMAOALRRK2 | |
| SCHEMBL29184295 | 0.90 | MAOB (0.44) | MAOBMEN1KMT2AMAOALRRK2 | |
| SCHEMBL28418060 | 0.87 | MAOA (0.49) | CFTRMAOBMEN1KMT2AMAOA | |
| SCHEMBL21644549 | 0.85 | MAOB (0.41) | MAOBMEN1KMT2AMAOALRRK2 | |
| SCHEMBL21644617 | 0.84 | LRRK2 (0.44) | MEN1KMT2ALRRK2GAASGMS2 | |
| SCHEMBL30779583 | 0.84 | LRRK2 (0.44) | MEN1KMT2ALRRK2GAASGMS2 | |
| SCHEMBL21644687 | 0.83 | SGMS2 (0.62) | MEN1KMT2ALRRK2GAASGMS2 | |
| SCHEMBL30779582 | 0.83 | SGMS2 (0.62) | MEN1KMT2ALRRK2GAASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |