Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.47 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644655 | 0.86 | HSP90AA1 (0.64) | SMN1; SMN2CYP2C19KMT2ALMNAHPGD | |
| SCHEMBL30779607 | 0.86 | HSP90AA1 (0.48) | POLBCNR2LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL21644589 | 0.86 | HSP90AA1 (0.48) | POLBCNR2LMNAHSP90AA1HSP90AB1 | |
| SCHEMBL25100417 | 0.85 | HDAC6 (0.66) | CYP1A2CYP2C19HSP90AA1HDAC3HDAC1 | |
| SCHEMBL29200006 | 0.82 | HSP90AA1 (0.70) | SMN1; SMN2CYP1A2CYP2C19KMT2AHSP90AA1 | |
| SCHEMBL21644546 | 0.80 | P2RX1 (0.56) | SMN1; SMN2POLBKMT2ALMNAHSP90AA1 | |
| SCHEMBL21644658 | 0.80 | HPGD (0.52) | KMT2ALMNAHPGDHSP90AA1HSP90AB1 | |
| SCHEMBL5078982 | 0.75 | L3MBTL1 (0.57) | SMN1; SMN2POLBCYP1A2CYP2C19KMT2A | |
| SCHEMBL21644646 | 0.75 | HSP90AA1 (0.77) | CYP1A2CYP2C19HSP90AA1HDAC3HDAC1 | |
| SCHEMBL5079089 | 0.75 | CNR2 (0.67) | SMN1; SMN2POLBCYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111164074-B | Heat shock protein 90 inhibitors | 台北医学大学 | 2024-02-02 | — | — | CN | disclosed |
| US-11479528-B2 | Heat shock protein 90 inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-10-25 | — | — | US | disclosed |
| CN-111164074-A | Heat shock protein 90 inhibitor | 台北医学大学 | 2020-05-15 | — | — | CN | disclosed |
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | SMN1; SMN2 4067/4885POLB 2443/4885CYP1A2 3098/4885 |
| US-11479528-B2 | Heat shock protein 90 inhibitors | HSP90AB1, HSP90AB2P, HSP90AA1 | SMN1; SMN2 4067/4885POLB 2443/4885CYP1A2 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.