Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079089 | 0.79 | CNR2 (0.67) | CNR2KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5080772 | 0.78 | CNR2 (0.51) | CNR2KMT2ASMN1; SMN2POLBHTT | |
| SCHEMBL12261441 | 0.77 | MKNK1 (0.44) | SMN1; SMN2LMNANPC1ALDH1A1RAB9A | |
| SCHEMBL12261505 | 0.77 | TGFBR1 (0.60) | CNR2KMT2A | |
| SCHEMBL19523059 | 0.76 | TGFBR1 (0.53) | CNR2SMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL21644656 | 0.75 | SMN1; SMN2 (0.53) | L3MBTL1CNR2KMT2ACYP1A2CYP2C19 | |
| SCHEMBL5452520 | 0.75 | CNR2 (0.84) | CNR2CYP1A2CYP2C19SMN1; SMN2POLB | |
| SCHEMBL16340385 | 0.74 | L3MBTL1 (0.57) | L3MBTL1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2735040 | 0.74 | KMT2A (0.87) | L3MBTL1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5083535 | 0.74 | CNR2 (0.51) | CNR2CYP1A2CYP2C19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | L3MBTL1 4731/4885CNR2 1/4885KMT2A 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.