Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483744 | 1.00 | SLC6A3 (0.38) | SLC6A3KMT2AMEN1EP300CREBBP | |
| SCHEMBL23440867 | 0.88 | SLC6A3 (0.39) | SLC6A3PTGER4 | |
| SCHEMBL23440869 | 0.88 | SLC6A3 (0.39) | SLC6A3PTGER4 | |
| SCHEMBL21647850 | 0.87 | FKBP1A (0.34) | SLC6A3KMT2AMEN1PTGER4 | |
| SCHEMBL29191833 | 0.87 | FKBP1A (0.34) | SLC6A3KMT2AMEN1PTGER4 | |
| SCHEMBL29483738 | 0.87 | FKBP1A (0.34) | SLC6A3KMT2AMEN1PTGER4 | |
| SCHEMBL29191834 | 0.86 | SLC6A3 (0.35) | SLC6A3KMT2AACEPTGER4ATM | |
| SCHEMBL21647801 | 0.81 | KIF11 (0.36) | SLC6A3PTGER4 | |
| SCHEMBL21647800 | 0.81 | KIF11 (0.36) | SLC6A3PTGER4 | |
| SCHEMBL30409321 | 0.81 | KIF11 (0.36) | SLC6A3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |