Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716399 | 0.82 | GRM5 (0.44) | GRM5GRM1SCN9A | |
| SCHEMBL2305787 | 0.81 | HSD17B10 (0.39) | CLK1DYRK1ADYRK1BTRPM8KMT2A | |
| SCHEMBL22715748 | 0.76 | MLYCD (0.39) | CLK1DYRK1ADYRK1BTRPM8MEN1 | |
| SCHEMBL1682676 | 0.75 | GRM5 (0.48) | GRM5MEN1KMT2A | |
| SCHEMBL3569043 | 0.75 | CLK1 (0.37) | CLK1DYRK1ADYRK1BTRPM8MEN1 | |
| SCHEMBL1706430 | 0.74 | — | — | |
| SCHEMBL15689109 | 0.72 | GRM5 (0.46) | GRM5MEN1KMT2A | |
| SCHEMBL15689239 | 0.72 | NPC1 (0.54) | MEN1KMT2ATDP1PTGS2GRM1 | |
| SCHEMBL8282923 | 0.70 | MLYCD (0.41) | CLK1DYRK1ADYRK1BTRPM8MEN1 | |
| SCHEMBL168669 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188023-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| US-12258308-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2025-03-25 | — | — | US | disclosed |
| CN-112513011-B | Benzene derivatives | 小野药品工业株式会社 | 2023-06-16 | — | — | CN | disclosed |
| US-20220089532-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-24 | — | — | US | disclosed |
| US-11261154-B2 | Benzene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210332009-A1 | BENZENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | US | disclosed |
| EP-3831810-A1 | BENZENE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2021-06-09 | — | — | EP | disclosed |
| CN-112513011-A | Benzene derivatives | 小野药品工业株式会社 | 2021-03-16 | — | — | CN | disclosed |
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258308-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | GRM5 2897/4885CLK1 4614/4885DYRK1A 4514/4885 |
| US-11261154-B2 | Benzene derivative | PMP22, TMBIM6, MYT1 | GRM5 2897/4885CLK1 4614/4885DYRK1A 4514/4885 |
| US-20250188023-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | GRM5 2881/4885CLK1 4618/4885DYRK1A 4494/4885 |
| US-20210332009-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | GRM5 2897/4885CLK1 4614/4885DYRK1A 4514/4885 |
| US-20220089532-A1 | BENZENE DERIVATIVE | PMP22, TMBIM6, MYT1 | GRM5 2897/4885CLK1 4614/4885DYRK1A 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.