Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.52 |
| ▸ | FABP1 | P07148 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SQSTM1 | Q13501 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647847 | 0.95 | FABP1 (0.53) | PTGDR2MCL1BCL2A1SLC16A3FABP1 | |
| SCHEMBL21647789 | 0.91 | PTGDR2 (0.64) | PTGDR2MCL1BCL2A1SLC16A3FABP1 | |
| SCHEMBL21647713 | 0.89 | FFAR1 (0.60) | MCL1BCL2A1SLC16A3TDP1L3MBTL1 | |
| SCHEMBL21647756 | 0.85 | FABP1 (0.64) | MCL1BCL2A1FABP1TDP1FFAR1 | |
| SCHEMBL31548946 | 0.85 | FABP1 (0.64) | MCL1BCL2A1FABP1TDP1FFAR1 | |
| SCHEMBL21647679 | 0.82 | LTB4R (0.51) | PTGDR2MCL1SLC16A3FABP1TDP1 | |
| SCHEMBL21647848 | 0.81 | FABP1 (0.67) | MCL1BCL2A1FABP1TDP1FFAR1 | |
| SCHEMBL31548985 | 0.81 | FABP1 (0.67) | MCL1BCL2A1FABP1TDP1FFAR1 | |
| SCHEMBL7425678 | 0.80 | ALDH1A1 (0.55) | MCL1SLC16A3NPC1RAB9ASQSTM1 | |
| SCHEMBL21647730 | 0.80 | LTB4R (0.51) | PTGDR2MCL1BCL2A1SLC16A3FABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |