Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | SQSTM1 | Q13501 | 2/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647679 | 0.95 | LTB4R (0.51) | LTB4RLTB4R2KEAP1NFE2L2SQSTM1 | |
| SCHEMBL21647703 | 0.90 | PTGDR2 (0.49) | LTB4RLTB4R2KEAP1NFE2L2SQSTM1 | |
| SCHEMBL7425678 | 0.87 | ALDH1A1 (0.55) | KEAP1NFE2L2SQSTM1SLC16A3TBXA2R | |
| SCHEMBL3554985 | 0.85 | TDP1 (0.53) | LTB4RLTB4R2KEAP1NFE2L2SQSTM1 | |
| SCHEMBL21647689 | 0.84 | TDP1 (0.47) | LTB4RLTB4R2KEAP1NFE2L2SQSTM1 | |
| SCHEMBL31548955 | 0.83 | FABP1 (0.56) | LTB4RLTB4R2KEAP1NFE2L2SQSTM1 | |
| SCHEMBL21647847 | 0.83 | FABP1 (0.53) | KEAP1NFE2L2SQSTM1TDP1SLC16A3 | |
| SCHEMBL21647732 | 0.83 | FABP1 (0.56) | LTB4RLTB4R2KEAP1NFE2L2SQSTM1 | |
| SCHEMBL21647713 | 0.82 | FFAR1 (0.60) | KEAP1NFE2L2SQSTM1TDP1SLC16A3 | |
| SCHEMBL3897238 | 0.80 | KEAP1 (0.55) | KEAP1NFE2L2SQSTM1TDP1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |