Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NCF1 | P14598 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659625 | 0.67 | HTT (0.46) | HTTLMNANCF1CYP1A2NOS2 | |
| SCHEMBL30824471 | 0.63 | HTT (0.47) | HTTLMNANCF1CYP1A2NOS2 | |
| SCHEMBL14940197 | 0.62 | NPC1 (0.45) | HTTLMNANCF1CYP1A2NOS2 | |
| SCHEMBL22127183 | 0.62 | NCF1 (0.47) | HTTLMNANCF1CYP1A2NOS2 | |
| SCHEMBL10083312 | 0.61 | MGAM (0.49) | HTTLMNAMGAMMAPTNPC1 | |
| SCHEMBL24281312 | 0.60 | KMT2A (0.54) | HTTLMNAALDH1A1NPSR1GAA | |
| SCHEMBL7648132 | 0.60 | NCF1 (0.54) | LMNANCF1CYP1A2NOS2BACE1 | |
| SCHEMBL4936198 | 0.59 | LMNA (0.39) | HTTLMNANCF1CYP1A2NOS2 | |
| SCHEMBL84064 | 0.59 | NCF1 (0.52) | LMNANCF1CYP1A2NOS2BACE1 | |
| SCHEMBL6140328 | 0.59 | NCF1 (0.52) | LMNANCF1CYP1A2NOS2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188635-B1 | QUANTIFICATION OF ANALYTES USING ACCELERATOR MASS SPECTROMETRY | XCELERON INC (US) | 2014-03-12 | — | — | EP | disclosed |
| US-7985589-B2 | Quantification of analytes using accelerator mass spectrometry | XCELERON, LIMITED (GB) | 2011-07-26 | — | — | US | disclosed |
| EP-2188635-A1 | QUANTIFICATION OF ANALYTES USING ACCELERATOR MASS SPECTROMETRY | Xceleron Limited (GB) | 2010-05-26 | — | — | EP | disclosed |
| US-20100120156-A1 | QUANTIFICATION OF ANALYTES USING ACCELERATOR MASS SPECTROMETRY | XCELERON, LIMITED | 2010-05-13 | — | — | US | disclosed |
| WO-2009010764-A1 | QUANTIFICATION OF ANALYTES USING ACCELERATOR MASS SPECTROMETRY | XCELERON LIMITED (GB) | 2009-01-22 | — | — | WO | disclosed |