Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267839 | 0.75 | CYSLTR1 (0.53) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL29374931 | 0.74 | RAB9A (0.64) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL170196 | 0.74 | RAB9A (0.64) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL31490600 | 0.72 | RAB9A (0.61) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL30883993 | 0.72 | RAB9A (0.61) | NCF1CYP1A2NOS2BACE1CA12 | |
| Hydrochloric Acid SCHEMBL31243061 | 0.72 | ALDH1A1 (0.63) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL30883995 | 0.72 | RAB9A (0.61) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL31365172 | 0.72 | RAB9A (0.61) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL34463709 | 0.72 | RAB9A (0.61) | NCF1CYP1A2NOS2BACE1CA12 | |
| SCHEMBL10866984 | 0.72 | RAB9A (0.61) | NCF1CYP1A2NOS2BACE1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100427513-C | Catalyst for polymerization or copolymerization of alpha-olefin, catalyst component therefor, and method for polymerization of alpha-olefin using the catalyst | UBE INDUSTRIES (JP) | 2008-10-22 | — | — | CN | disclosed |
| CN-1244585-C | Synthesis of silyl camptothecins and silyl homo camptothecins | UNIV PITTSBURGH (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1675255-A | Catalyst for polymerization or copolymerization of alpha-olefin, catalyst component therefor, and method for polymerization of alpha-olefin using the catalyst | UBE INDUSTRIES (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1514841-A | Synthesis of silyl camptothecins and silyl homo camptothecins | ƥ�ȱ���ѧ | 2004-07-21 | — | — | CN | disclosed |
| WO-2002083694-A1 | SYNTHESIS OF SILYL CAMPTOTHECINS AND SILYL HOMOCAMPTOTHECINS | UNIVERSITY OF PITTSBURGH (US) | 2002-10-24 | — | — | WO | disclosed |
| US-6372906-B1 | REACTING CAMPTOTHECIN OR HOMOCAMPTOTHECIN WITH SILYL RADICAL PRECURSOR UNDER CONDITIONS TO GENERATE SILYL RADICAL | UNIVERSITY OF PITTSBURGH | 2002-04-16 | — | — | US | disclosed |
| EP-0206751-A2 | 2-Substituted quinolines, their preparation and use | MERCK FROSST CANADA INC. (CA) | 1986-12-30 | — | — | EP | disclosed |