Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26484643 | 0.88 | ALDH1A1 (0.42) | KMT2AMEN1MCHR1MAPK14CTRB1 | |
| SCHEMBL31066573 | 0.88 | CTRB1 (0.55) | MAPK14CTRB1FAAH | |
| SCHEMBL31066644 | 0.85 | NPC1 (0.48) | MCHR1NR1H4CTRB1 | |
| SCHEMBL21634140 | 0.85 | NPC1 (0.48) | MCHR1NR1H4CTRB1 | |
| SCHEMBL1255936 | 0.85 | MAPK14 (0.55) | KMT2AMEN1MAPK14 | |
| SCHEMBL21634096 | 0.84 | POLB (0.46) | KMT2AMEN1MCHR1FAAH | |
| SCHEMBL31066580 | 0.84 | POLB (0.46) | KMT2AMEN1MCHR1FAAH | |
| SCHEMBL14576364 | 0.80 | MAPK8 (0.48) | KMT2AMEN1MAPK14MRGPRX4 | |
| SCHEMBL20503971 | 0.78 | FLT1 (0.48) | KMT2AMAPK14CYP1A2 | |
| SCHEMBL13522479 | 0.78 | MAPT (0.51) | KMT2AMEN1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022794-A1 | 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2020-01-30 | — | — | WO | disclosed |