SCHEMBL21650697

SCHEMBL21650697

CC(N)c1cccc2oc3ccccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
KDM4E B2RXH2 5/20 0.41
HPGD P15428 5/20 0.41
HSD17B10 Q99714 4/20 0.41
MAOA P21397 3/20 0.41
GLA P06280 3/20 0.41
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CYP3A4 P08684 2/20 0.41
PGAM1 P18669 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
PNMT P11086 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24383960 0.85 MAOA (0.48) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL1102418 0.85 HPGD (0.43) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL23056897 0.79 TSHR (0.47) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL21671610 0.78 ALOX5 (0.49) ALDH1A1KDM4EHPGDMAOAMAPT
SCHEMBL27854627 0.77 MAOA (0.37) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL22434080 0.77 MAOA (0.46) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL11204321 0.76 MAOA (0.42) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL24626620 0.76 NQO1 (0.42) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL2195718 0.75 MAOA (0.54) ALDH1A1KDM4EHPGDHSD17B10MAOA
SCHEMBL24501824 0.75 TDP1 (0.40) ALDH1A1KDM4EHPGDHSD17B10MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020022769-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-01-30 WO disclosed