Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | CDC14B | O60729 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943956 | 0.89 | MAOA (0.54) | MAOAKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL11204325 | 0.83 | ALOX5 (0.43) | MAOACXCL8KDM4EUSP2CSNK2A2 | |
| SCHEMBL9407687 | 0.81 | MAOA (0.42) | MAOAKDM4EUSP2CSNK2A2PTGS1 | |
| SCHEMBL6601227 | 0.80 | CYP2C9 (0.42) | MAOAKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL1102418 | 0.79 | HPGD (0.43) | MAOAKDM4EPTGS1SMN1; SMN2NPC1 | |
| SCHEMBL27318902 | 0.79 | MAOA (0.55) | MAOAKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL1066709 | 0.77 | MMP12 (0.39) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL21650697 | 0.76 | ALDH1A1 (0.41) | MAOAKDM4EUSP2SMN1; SMN2NPC1 | |
| SCHEMBL9764857 | 0.76 | ALOX5 (0.59) | ALDH1A1GLA | |
| SCHEMBL22434080 | 0.75 | MAOA (0.46) | MAOAKDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068563-A2 | Heterocyclic acetic acid compounds and compositions for treating bone diseases | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |