Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.55 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620324 | 0.83 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17803532 | 0.83 | MEN1 (0.66) | KCNK9NPC1RAB9ASMN1; SMN2KCNK3 | |
| SCHEMBL23352871 | 0.81 | TRPV1 (0.68) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL7303163 | 0.81 | HDAC3 (0.86) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL1687868 | 0.80 | TRPV1 (0.76) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL16678174 | 0.80 | HDAC3 (0.73) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL21652312 | 0.80 | TRPV1 (0.76) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL7300689 | 0.80 | KCNK3 (0.64) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL7301130 | 0.80 | TRPV1 (0.76) | TRPV1HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL16677863 | 0.80 | HDAC6 (0.73) | TRPV1HDAC3HDAC6HDAC8HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | TRPV1 4344/4885HDAC3 3413/4885HDAC6 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.