Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653164 | 0.84 | MAPT (0.37) | MAPTMAPK1MEN1KMT2AFSCN1 | |
| SCHEMBL21653130 | 0.81 | MAPT (0.35) | MAPTMAPK1MEN1KMT2AFSCN1 | |
| SCHEMBL21652862 | 0.81 | MAPT (0.32) | MAPTMAPK1MEN1KMT2A | |
| SCHEMBL21653256 | 0.79 | MAPT (0.34) | MAPTMAPK1MEN1KMT2AFSCN1 | |
| SCHEMBL21653148 | 0.78 | MAPT (0.36) | MAPTMAPK1MEN1KMT2AFSCN1 | |
| SCHEMBL21653248 | 0.78 | MET (0.34) | MAPTMAPK1MEN1KMT2A | |
| SCHEMBL21653131 | 0.78 | MAPT (0.35) | MAPTMAPK1MEN1KMT2AFSCN1 | |
| SCHEMBL21653244 | 0.76 | BACE1 (0.39) | MAPTMAPK1MEN1KMT2AFSCN1 | |
| SCHEMBL21653074 | 0.75 | GSK3B (0.38) | MAPTMAPK1MEN1KMT2A | |
| SCHEMBL21652914 | 0.74 | MAPT (0.31) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |