Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653177 | 0.88 | MAPT (0.46) | ALDH1A1RXFP1RAB9ANPC1MAPT | |
| SCHEMBL21653182 | 0.84 | KMT2A (0.52) | RAB9ANPC1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL21653176 | 0.84 | MEN1 (0.58) | RAB9ANPC1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL21653184 | 0.83 | KCNQ3 (0.53) | RAB9ANPC1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL21653193 | 0.81 | KCNQ3 (0.53) | RAB9ANPC1KCNQ3KCNQ2KCNE1 | |
| SCHEMBL21653246 | 0.80 | MAPT (0.43) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL21652920 | 0.79 | MAPT (0.42) | RAB9ANPC1MAPTTP53MEN1 | |
| SCHEMBL21653070 | 0.78 | MEN1 (0.44) | ALDH1A1RXFP1RAB9ANPC1MAPT | |
| SCHEMBL28708129 | 0.78 | KCNK3 (0.59) | ALDH1A1KCNK3KCNK9RXFP1RAB9A | |
| SCHEMBL29389710 | 0.78 | KCNK3 (0.59) | ALDH1A1KCNK3KCNK9RXFP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |