Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 8/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653160 | 0.92 | MEN1 (0.35) | MAPTMAPK1ARIDO1MEN1 | |
| SCHEMBL21653151 | 0.90 | PDE10A (0.35) | MAPTMAPK1ARENPP2MEN1 | |
| SCHEMBL21653256 | 0.87 | MAPT (0.34) | MAPTMAPK1ARENPP2MEN1 | |
| SCHEMBL21653146 | 0.87 | MET (0.33) | MAPTMAPK1ARENPP2KMT2A | |
| SCHEMBL21653264 | 0.86 | MAPT (0.36) | MAPTMAPK1ARMEN1KMT2A | |
| SCHEMBL21653143 | 0.85 | MAPT (0.36) | MAPTMAPK1ARMEN1KMT2A | |
| SCHEMBL21653277 | 0.84 | AR (0.35) | MAPTMAPK1ARMEN1KMT2A | |
| SCHEMBL21633859 | 0.81 | LRRK2 (0.38) | AR | |
| SCHEMBL21653050 | 0.79 | AR (0.35) | MAPTMAPK1AR | |
| SCHEMBL21653072 | 0.78 | KMT2A (0.38) | MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |