Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653146 | 0.87 | MET (0.33) | METAXLMAPTMAPK1TP53 | |
| SCHEMBL21653041 | 0.87 | MAPT (0.34) | METAXLMAPTMAPK1TP53 | |
| SCHEMBL21652918 | 0.84 | GSK3B (0.36) | METAXLMAPTMAPK1TP53 | |
| SCHEMBL21653248 | 0.82 | MET (0.34) | METAXLMAPTMAPK1TP53 | |
| SCHEMBL21653326 | 0.82 | CYP2C9 (0.40) | METAXLMAPTMAPK1 | |
| SCHEMBL21633837 | 0.80 | MAPT (0.39) | METAXLMAPTMAPK1 | |
| SCHEMBL21653010 | 0.78 | MEN1 (0.32) | METAXLMAPTMAPK1 | |
| SCHEMBL21653050 | 0.77 | AR (0.35) | MAPTMAPK1TP53 | |
| SCHEMBL21652863 | 0.76 | MAPT (0.32) | METAXLMAPT | |
| SCHEMBL21653151 | 0.76 | PDE10A (0.35) | MAPTMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |