Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 13/20 | 0.68 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653955 | 0.87 | BRS3 (0.61) | BRS3LTB4R2LPAR1 | |
| SCHEMBL3230323 | 0.83 | LTB4R2 (0.63) | BRS3LTB4R2 | |
| SCHEMBL5937181 | 0.82 | BRS3 (0.58) | BRS3LTB4R2LPAR1 | |
| SCHEMBL10902221 | 0.80 | LTB4R2 (0.60) | BRS3LTB4R2 | |
| SCHEMBL3906504 | 0.80 | BRS3 (0.70) | BRS3LTB4R2LPAR1 | |
| SCHEMBL202160 | 0.79 | LTB4R2 (0.61) | LTB4R2 | |
| SCHEMBL21653954 | 0.79 | BRS3 (0.70) | BRS3LTB4R2LPAR1 | |
| SCHEMBL5151244 | 0.79 | LTB4R2 (0.60) | BRS3LTB4R2LPAR1 | |
| SCHEMBL18759613 | 0.78 | HNF4A (0.63) | LTB4R2 | |
| SCHEMBL30292805 | 0.78 | HNF4A (0.63) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-06-22 | — | — | US | disclosed |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-05-04 | — | — | US | disclosed |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2021-01-14 | — | — | US | disclosed |
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | FURIN, PEPD, PIN1 | BRS3 4429/4885LTB4R2 2966/4885LPAR1 3974/4885 |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | FURIN, PEPD, PIN1 | BRS3 4429/4885LTB4R2 2966/4885LPAR1 3974/4885 |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | TPMT, MAPT, TLR4 | BRS3 2130/4885LTB4R2 1534/4885LPAR1 2922/4885 |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | TPMT, PBRM1, PGM2 | BRS3 1496/4885LTB4R2 2646/4885LPAR1 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.