Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8098694 | 0.92 | TSHR (0.50) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Sulfuric Acid SCHEMBL8362452 | 0.91 | TSHR (0.49) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| SCHEMBL758619 | 0.87 | TSHR (0.59) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Acetic Acid SCHEMBL22188618 | 0.85 | TSHR (0.53) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Bromide SCHEMBL1254317 | 0.85 | TSHR (0.57) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Fluoride Ion SCHEMBL1254970 | 0.85 | TSHR (0.57) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Iodide SCHEMBL1255392 | 0.85 | TSHR (0.57) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Hydrochloric Acid SCHEMBL204258 | 0.85 | TSHR (0.57) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Hydrochloric Acid SCHEMBL534137 | 0.85 | TSHR (0.57) | TSHRSLC22A16ALDH1A1THRBMAPT | |
| Chloromethane SCHEMBL10796929 | 0.84 | TSHR (0.55) | TSHRSLC22A16ALDH1A1THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003585-B2 | Cationic polymers and fixative applications therefor | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| EP-2340263-A1 | CATIONIC POLYMERS AND FIXATIVE APPLICATIONS THEREFOR | Lubrizol Advanced Materials, Inc. (US) | 2011-07-06 | — | — | EP | disclosed |
| WO-2010033302-A9 | CATIONIC POLYMERS AND FIXATIVE APPLICATIONS THEREFOR | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100284955-A1 | Cationic Polymers And Fixative Applications Therefor | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-7759296-B2 | Cationic polymers and fixative application therefor | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| WO-2010033302-A1 | CATIONIC POLYMERS AND FIXATIVE APPLICATIONS THEREFOR | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20090010855-A1 | Cationic Polymers And Fixative Applications Therefor | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| EP-0869169-B1 | Detergent composition | NAT STARCH AND CHEMICALINVEST (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-0879793-B1 | A process for treating water to inhibit scale formation | NAT STARCH AND CHEMICALINVEST (US) | 2004-01-02 | — | — | EP | disclosed |
| EP-0608845-B1 | Multifunctional maleate polymers | NAT STARCH CHEM INVEST (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0608845-A2 | Multifunctional maleate polymers | National Starch and Chemical Investment Holding Corporation (US) | 1994-08-03 | — | — | EP | disclosed |
| US-5294692-A | Butylene oxide-ethylene oxide copolymers modified with isocyanatoalkyl acrylates for coatings, sizing, drilling fluid or detergents | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5180473-A | Cationic Polymer Retention Aid | MITSUI-CYANAMID, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5132285-A | Or enhancing water retention, graft copolymerizing a polysaccharide with a cationic/anionic monomer pair or a zwitterionic monomer, thermal initiator, dispersing resultant polyampholyte in aqueous media | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5132284-A | Thickeners, stabilizers; papermaking, oil drilling; guar gum | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0216091-B1 | INVERSE EMULSIONS | National Starch and Chemical Investment Holding Corporation (US) | 1992-05-06 | — | — | EP | disclosed |
| EP-0339372-A2 | Method and composition for thickening or stabilizing aqueous media with polyamphoteric polysaccharides | National Starch and Chemical Investment Holding Corporation (US) | 1989-11-02 | — | — | EP | disclosed |
| US-4690996-A | CONTAINING A POLYSACCHARIDE GRAFT COPOLYMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |
| US-4152307-A | FLOCCULANTS | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1979-05-01 | — | — | US | disclosed |
| US-4131576-A | Process for the preparation of graft copolymers of a water soluble monomer and polysaccharide employing a two-phase reaction system | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090010855-A1 | Cationic Polymers And Fixative Applications Therefor | CTSL, CATSPER1, HASPIN | CHRM1 3219/4885TSHR 2175/4885SLC22A16 721/4885 |
| US-20100284955-A1 | Cationic Polymers And Fixative Applications Therefor | CTSL, CATSPER1, HASPIN | CHRM1 3219/4885TSHR 2175/4885SLC22A16 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.