SCHEMBL21656510

SCHEMBL21656510

CCCCCc1ccc(Oc2ccc(C(=O)O)cn2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.56
CYSLTR1 Q9Y271 1/20 0.56
RARB P10826 7/20 0.56
OPRM1 P35372 7/20 0.55
OPRD1 P41143 7/20 0.55
OPRK1 P41145 6/20 0.55
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
ALDH1A1 P00352 1/20 0.55
RARA P10276 1/20 0.55
MTOR P42345 1/20 0.55
KMT2A Q03164 1/20 0.55
NPC1 O15118 1/20 0.53
NFKB1 P19838 1/20 0.53
RAB9A P51151 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PLA2G4A P47712 1/20 0.51
GRIN2D O15399 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21656855 0.99 RARB (0.57) GRM2CYSLTR1RARBOPRM1OPRD1
SCHEMBL21656822 0.96 GRM2 (0.57) GRM2CYSLTR1RARBOPRM1OPRD1
SCHEMBL21628768 0.91 GRM2 (0.62) GRM2CYSLTR1OPRM1OPRD1OPRK1
SCHEMBL21628719 0.89 OPRM1 (0.65) OPRM1OPRD1OPRK1GRIN2DGRIN3B
SCHEMBL21628559 0.88 OPRM1 (0.64) OPRM1OPRD1OPRK1GRIN2DGRIN3B
SCHEMBL21656861 0.88 MAPT (0.56) OPRM1OPRD1OPRK1MAPTSMN1; SMN2
SCHEMBL21628571 0.86 OPRM1 (0.65) OPRM1OPRD1OPRK1SMN1; SMN2PLA2G4A
SCHEMBL21656682 0.86 MAPT (0.55) OPRM1OPRD1OPRK1MAPTSMN1; SMN2
SCHEMBL21628729 0.86 OPRM1 (0.49) GRM2CYSLTR1OPRM1OPRD1OPRK1
SCHEMBL21656689 0.86 PDE4B (0.52) GRM2CYSLTR1OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK GRM2 4777/4885CYSLTR1 2413/4885RARB 1144/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK GRM2 4787/4885CYSLTR1 2381/4885RARB 1064/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK GRM2 4777/4885CYSLTR1 2413/4885RARB 1144/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR GRM2 4083/4885CYSLTR1 1537/4885RARB 1531/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK GRM2 4777/4885CYSLTR1 2413/4885RARB 1144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.