Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 3/20 | 0.32 |
| ▸ | USP7 | Q93009 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108696 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1POLBGAAUSP8 | |
| SCHEMBL30450356 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1POLBGAAUSP8 | |
| SCHEMBL2708620 | 0.76 | RPS6KA5 (0.39) | CSNK1A1CLK4KDM4EALDH1A1POLB | |
| Ammonia Solution, Strong SCHEMBL28870434 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1POLBGAAUSP8 | |
| SCHEMBL15431202 | 0.75 | GRM5 (0.34) | PIK3CDSIRT2IDO1 | |
| SCHEMBL28457319 | 0.75 | SIRT2 (0.32) | PIK3CDSIRT2IDO1 | |
| SCHEMBL10960474 | 0.74 | KDM4E (0.33) | SIRT2KDM4EALDH1A1POLBGAA | |
| SCHEMBL21816291 | 0.74 | GRM5 (0.46) | PIK3CDCLK4KDM4EALDH1A1POLB | |
| SCHEMBL21248120 | 0.74 | PIK3CD (0.33) | PIK3CDKHKUSP8USP7ADORA2A | |
| SCHEMBL12665887 | 0.74 | PIK3CD (0.33) | PIK3CDKDM4EUSP8ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122055367-A | 5-Oxo-4, 5-dihydroimidazo [1,5-a ] quinazoline compounds as PI3K [ alpha ] inhibitors | 皮卡维森治疗学股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | JANSSEN PHARMACEUTICA NV (BE) | 2026-05-05 | — | — | US | disclosed |
| US-20250270213-A1 | PI3Ka INHIBITORS | PIKAVATION THERAPEUTICS, INC. | 2025-08-28 | — | — | US | disclosed |
| WO-2025085474-A1 | 5-OXO-4,5-DIHYDROIMIDAZO[1,5-A]QUINAZOLINE COMPOUNDS AS PI3K[ALPHA] INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| CN-114269720-B | Acetyl-coa synthetase short chain2(ACSS2) Small molecule inhibitors of (a) | 库拉德夫制药私人有限公司 | 2025-03-28 | — | — | CN | disclosed |
| EP-4522608-A1 | PYRROLIDINONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN Pharmaceutica NV (BE) | 2025-03-19 | — | — | EP | disclosed |
| CN-119654321-A | PI3K alpha inhibitors | 突触活化疗法股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| EP-4511373-A1 | PI3K? INHIBITORS | Synnovation Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| EP-4482831-A1 | NOVEL BICYCLIC COMPOUNDS AS RAD51 INHIBITORS | Satya Therapeutics, Inc. (US) | 2025-01-01 | — | — | EP | disclosed |
| CN-1349412-A | Cyclic therapy using cyclic urea and cyclic amide derivatives | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| US-6369056-B1 | AGONISTS AND ANTAGONISTS OF THE PROGESTERONE RECEPTOR; CONTRACEPTIVES; 6-(3-CHLOROPHENYL)-4,4-DIMETHYL-1,4-DIHYDRO -3-OXA-1,8-DIAZA-NAPHTHALENE-2-ONE AND 6-CHLORO-4,4-DIMETHYL-1,4-DIHYDRO-3-OXA-1,5-DIAZA-NAPHTHALEN-2-ONE | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-09 | — | — | US | disclosed |
| EP-1173208-A2 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC UREA AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-01-23 | — | — | EP | disclosed |
| EP-1173443-A1 | CYCLIC UREA AND CYCLIC AMIDE DERIVATIVES | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066103-A2 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC UREA AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000066592-A1 | CYCLIC UREA AND CYCLIC AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617789-B2 | Small molecular inhibitors of NF-κb inducing kinase | IRAK3, IKBKB, IKBKG | PIK3CD 511/4885CSNK1A1 301/4885CLK4 1068/4885 |
| US-20250270213-A1 | PI3Ka INHIBITORS | PIK3CA, PIK3C2A, PIK3R5 | PIK3CD 4/4885CSNK1A1 358/4885CLK4 3046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.