SCHEMBL30450356

SCHEMBL30450356

N#Cc1nc(Cl)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 4/20 0.39
POLB P06746 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
PSMB8 P28062 4/20 0.36
ALOX15 P16050 3/20 0.36
MBOAT4 Q96T53 1/20 0.35
USP8 P40818 2/20 0.33
USP7 Q93009 2/20 0.33
KMO O15229 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ERBB2 P04626 1/20 0.33
USP47 Q96K76 1/20 0.33
BCAT1 P54687 1/20 0.33
PSMB5 P28074 1/20 0.32
GAA P10253 2/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108696 1.00 KDM4E (0.39) KDM4EALDH1A1POLBCRHBPCRHR2
Ammonia Solution, Strong SCHEMBL28870434 0.98 KDM4E (0.38) KDM4EALDH1A1POLBCRHBPCRHR2
SCHEMBL31661428 0.82 MBOAT4 (0.39) KDM4EALDH1A1POLBPSMB8ALOX15
SCHEMBL2708620 0.79 RPS6KA5 (0.39) KDM4EALDH1A1POLBMBOAT4USP8
SCHEMBL2792945 0.79 KDM4E (0.38) KDM4EALDH1A1POLBPSMB8ALOX15
SCHEMBL10960474 0.77 KDM4E (0.33) KDM4EALDH1A1POLBALOX15USP8
SCHEMBL1006497 0.77 KDM4E (0.33) KDM4EALDH1A1POLBALOX15MBOAT4
SCHEMBL31167609 0.77 ALDH1A1 (0.41) KDM4EALDH1A1POLBALOX15USP8
SCHEMBL3399707 0.77 KHK (0.36) KDM4EALDH1A1POLBPSMB8ALOX15
SCHEMBL13291167 0.77 ALDH1A1 (0.33) KDM4EALDH1A1POLBALOX15USP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119410626-A Magnetic nitrilase catalyst for green cyclic synthesis of organic acid, preparation method and application thereof 浙江工业大学 2025-02-11 CN disclosed
CN-119193553-A Nitrilase mutant containing unnatural amino acid, coding gene, recombinant vector, recombinant strain and application thereof 浙江工业大学 2024-12-27 CN disclosed
CN-117683042-A Fused tetracyclic compound, preparation method thereof and application thereof in medicines 江苏恒瑞医药股份有限公司 2024-03-12 CN disclosed
CN-113912533-B Method for preparing 3, 6-dichloropicolinic acid 西安凯立新材料股份有限公司 2023-06-20 CN disclosed