Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 2/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30450356 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1POLBCRHBPCRHR2 | |
| Ammonia Solution, Strong SCHEMBL28870434 | 0.98 | KDM4E (0.38) | KDM4EALDH1A1POLBCRHBPCRHR2 | |
| SCHEMBL31661428 | 0.82 | MBOAT4 (0.39) | KDM4EALDH1A1POLBPSMB8ALOX15 | |
| SCHEMBL2708620 | 0.79 | RPS6KA5 (0.39) | KDM4EALDH1A1POLBMBOAT4USP8 | |
| SCHEMBL2792945 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1POLBPSMB8ALOX15 | |
| SCHEMBL10960474 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1POLBALOX15USP8 | |
| SCHEMBL1006497 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1POLBALOX15MBOAT4 | |
| SCHEMBL31167609 | 0.77 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBALOX15USP8 | |
| SCHEMBL3399707 | 0.77 | KHK (0.36) | KDM4EALDH1A1POLBPSMB8ALOX15 | |
| SCHEMBL13291167 | 0.77 | ALDH1A1 (0.33) | KDM4EALDH1A1POLBALOX15USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243027-B | A kind of preparation method of 3,6- dichloro-2-pyridyl carboxylic acid | 南京红太阳生物化学有限责任公司 | 2019-03-05 | — | — | CN | claimed |
| CN-106243027-A | A kind of preparation method of 3,6 dichloro 2 picolinic acids | 南京红太阳生物化学有限责任公司 | 2016-12-21 | — | — | CN | claimed |
| US-4766219-A | Preparation of 2-cyano-6-chloropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | claimed |
| EP-4709480-A1 | 5,6-FUSED BICYCLIC AMIDES AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS | Amgen Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| CN-113912533-B | Method for preparing 3, 6-dichloropicolinic acid | 西安凯立新材料股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-113912533-A | Method for preparing 3, 6-dichloropicolinic acid | 西安凯立新材料股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-10617675-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-14 | — | — | US | disclosed |
| CN-106243027-B | A kind of preparation method of 3,6- dichloro-2-pyridyl carboxylic acid | 南京红太阳生物化学有限责任公司 | 2019-03-05 | — | — | CN | disclosed |
| US-20180221342-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-08-09 | — | — | US | disclosed |
| US-9994591-B2 | Oxadiazolopyridine derivates for use as ghrelin O-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20180037594-A1 | Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors | BOEHRINGER INGELHEIM INERNATIONAL GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| US-6043282-A | FUNGICIDES, PESTICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0949248-A1 | 6-(NONSUBSTITUTED OR SUBSTITUTED) PHENOXYPICOLINIC ACIDS, PROCESS OF PREPARING THE SAME, AND AGRICULTURAL/HORTICULTURAL GERMICIDES CONTAINING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0882025-A1 | PYRIMIDINE DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PESTICIDES OR FUNGICIDES CONTAINING THESE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-09 | — | — | EP | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |
| WO-1997029093-A1 | PYRIMIDINE DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PESTICIDES OR FUNGICIDES CONTAINING THESE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-14 | — | — | WO | disclosed |
| US-4766219-A | Preparation of 2-cyano-6-chloropyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| US-4558134-A | PICORNAVIRUS | THE DOW CHEMICAL COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4008326-A | INCREASING PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037594-A1 | Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors | MBOAT4, GIPR, ACAT1 | KDM4E 1715/4885ALDH1A1 223/4885POLB 4574/4885 |
| US-10617675-B2 | Hepatitis C virus inhibitors | HAVCR2, MAVS, EIF2AK2 | KDM4E 3572/4885ALDH1A1 3966/4885POLB 2041/4885 |
| US-20180221342-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, MAVS, EIF2AK2 | KDM4E 3572/4885ALDH1A1 3966/4885POLB 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.