SCHEMBL21657760

SCHEMBL21657760

C=CC(=O)OCCCNC(=O)c1cc(NC(=O)c2ccc(/N=N/C(C(C)=O)C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cc2)cc(C(=O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.36
MAPT P10636 6/20 0.36
KDM4E B2RXH2 3/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 2/20 0.36
RXFP1 Q9HBX9 1/20 0.35
TP53 P04637 1/20 0.35
ALDH1A1 P00352 4/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.33
THRB P10828 1/20 0.32
RAB9A P51151 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657762 0.91 RXFP1 (0.36) PAX8MAPTKDM4EMAPK1KMT2A
SCHEMBL21657763 0.91 RXFP1 (0.36) PAX8MAPTKDM4EMAPK1KMT2A
SCHEMBL21657767 0.91 MAPT (0.35) PAX8MAPTKDM4EMAPK1KMT2A
SCHEMBL21657904 0.85 RXFP1 (0.36) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL23786268 0.85 MAPT (0.47) MAPTKDM4EMAPK1KMT2ATP53
SCHEMBL12014052 0.85 MAPT (0.47) MAPTKDM4EMAPK1KMT2ATP53
SCHEMBL15417576 0.84 MAPT (0.43) PAX8MAPTKDM4EMAPK1KMT2A
SCHEMBL21657899 0.84 MAPT (0.38) PAX8MAPTKDM4EMAPK1KMT2A
SCHEMBL10095178 0.83 MAPT (0.41) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL23786267 0.82 RXFP1 (0.44) PAX8MAPTKDM4EMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518827-B2 Curable composition, method for producing curable composition, film, color filter, method for manufacturing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210122850-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURABLE COMPOSITION, FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
WO-2020022247-A1 CURABLE COMPOSITION, PRODUCTION METHOD FOR CURABLE COMPOSITION, FILM, COLOR FILTER, PRODUCTION METHOD FOR COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-01-30 WO disclosed