SCHEMBL21657767

SCHEMBL21657767

C=CC(=O)OCCN(CCCNC(=O)c1cc(NC(=O)c2ccc(/N=N/C(C(C)=O)C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cc2)cc(C(=O)NCCCN(CCOC(=O)C=C)CCOC(=O)C=C)c1)CCOC(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 3/20 0.35
RXFP1 Q9HBX9 1/20 0.34
TP53 P04637 1/20 0.34
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
PAX8 Q06710 1/20 0.33
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
RAB9A P51151 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657763 0.92 RXFP1 (0.36) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL21657760 0.91 PAX8 (0.36) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL3337608 0.88 HDAC3 (0.41) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL5535292 0.88 HDAC3 (0.41) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL3337620 0.88 HDAC3 (0.41) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL21657762 0.86 RXFP1 (0.36) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL10095178 0.86 MAPT (0.41) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL6733383 0.86 HDAC3 (0.36) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL12961232 0.84 HDAC3 (0.45) MAPTKDM4EMAPK1KMT2ARXFP1
SCHEMBL22760571 0.83 RXFP1 (0.39) MAPTKDM4EMAPK1KMT2ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518827-B2 Curable composition, method for producing curable composition, film, color filter, method for manufacturing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210122850-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURABLE COMPOSITION, FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
WO-2020022247-A1 CURABLE COMPOSITION, PRODUCTION METHOD FOR CURABLE COMPOSITION, FILM, COLOR FILTER, PRODUCTION METHOD FOR COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-01-30 WO disclosed