SCHEMBL21657763

SCHEMBL21657763

C=CC(=O)OCCCNC(=O)c1cc(NC(=O)c2ccc(/N=N/C(C(C)=O)C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cc2)cc(C(=O)NCCCCN(CC)CC)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.36
MAPT P10636 4/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 3/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
POLB P06746 2/20 0.33
PAX8 Q06710 1/20 0.33
IGF1R P08069 2/20 0.32
ALDH1A1 P00352 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657767 0.92 MAPT (0.35) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL21657760 0.91 PAX8 (0.36) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL3337608 0.90 HDAC3 (0.41) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL5535292 0.90 HDAC3 (0.41) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL3337620 0.90 HDAC3 (0.41) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL21657766 0.89 RXFP1 (0.44) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL6733383 0.89 HDAC3 (0.36) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL21657762 0.88 RXFP1 (0.36) RXFP1MAPTKDM4EMAPK1KMT2A
SCHEMBL14756618 0.86 MAPT (0.41) MAPTKDM4EMAPK1KMT2AALDH1A1
SCHEMBL12961232 0.86 HDAC3 (0.45) RXFP1MAPTKDM4EMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518827-B2 Curable composition, method for producing curable composition, film, color filter, method for manufacturing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210122850-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURABLE COMPOSITION, FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
WO-2020022247-A1 CURABLE COMPOSITION, PRODUCTION METHOD FOR CURABLE COMPOSITION, FILM, COLOR FILTER, PRODUCTION METHOD FOR COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-01-30 WO disclosed