SCHEMBL21657762

SCHEMBL21657762

C=CC(=O)OCCCNC(=O)c1cc(NC(=O)c2ccc(/N=N/C(C(C)=O)C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cc2)cc(C(=O)OCCCS(=O)(=O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.36
KMT2A Q03164 3/20 0.35
MAPT P10636 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 2/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 2/20 0.32
PAX8 Q06710 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
TP53 P04637 1/20 0.32
RAB9A P51151 1/20 0.31
MEN1 O00255 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657904 0.94 RXFP1 (0.36) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL21657760 0.91 PAX8 (0.36) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL23786267 0.88 RXFP1 (0.44) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL21657763 0.88 RXFP1 (0.36) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL21657767 0.86 MAPT (0.35) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL14756618 0.80 MAPT (0.41) KMT2AMAPTALDH1A1MAPK1GAA
SCHEMBL10095178 0.79 MAPT (0.41) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL14747278 0.78 MAPT (0.40) KMT2AMAPTALDH1A1MAPK1GAA
SCHEMBL3337620 0.78 HDAC3 (0.41) RXFP1KMT2AMAPTALDH1A1MAPK1
SCHEMBL5535292 0.78 HDAC3 (0.41) RXFP1KMT2AMAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518827-B2 Curable composition, method for producing curable composition, film, color filter, method for manufacturing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210122850-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURABLE COMPOSITION, FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
WO-2020022247-A1 CURABLE COMPOSITION, PRODUCTION METHOD FOR CURABLE COMPOSITION, FILM, COLOR FILTER, PRODUCTION METHOD FOR COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-01-30 WO disclosed