SCHEMBL21657765

SCHEMBL21657765

C=CC(=O)OCCCNC(=O)c1cc(NC(=O)CCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc(C(=O)NCCCCN(CC)CC)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
HDAC3 O15379 2/20 0.42
HDAC4 P56524 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC7 Q8WUI4 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC10 Q969S8 2/20 0.42
HDAC11 Q96DB2 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
HDAC9 Q9UKV0 2/20 0.42
HDAC5 Q9UQL6 2/20 0.42
TERT O14746 2/20 0.41
RXFP1 Q9HBX9 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
NPC1 O15118 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21657766 0.93 RXFP1 (0.44) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL21657902 0.83 HDAC3 (0.41) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL23306827 0.83 HDAC3 (0.41) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL21657763 0.83 RXFP1 (0.36) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL19012214 0.78 MAPT (0.47) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL21657768 0.76 POLB (0.38) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL21657903 0.76 RXFP1 (0.42) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL23306823 0.76 GRIN1 (0.44) MAPTTERTTDP1POLB
SCHEMBL23786265 0.75 KDM4E (0.46) MAPTHDAC3HDAC4HDAC1HDAC7
SCHEMBL23306815 0.75 TDP1 (0.45) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518827-B2 Curable composition, method for producing curable composition, film, color filter, method for manufacturing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210122850-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURABLE COMPOSITION, FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
WO-2020022247-A1 CURABLE COMPOSITION, PRODUCTION METHOD FOR CURABLE COMPOSITION, FILM, COLOR FILTER, PRODUCTION METHOD FOR COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-01-30 WO disclosed