SCHEMBL21657768

SCHEMBL21657768

C=CC(=O)OCCCNC(=O)c1cc(NC(=O)c2ccc(C3=C4C(=O)NC(c5ccc(C(=O)Nc6cc(C(=O)NCCCCN(CC)CC)cc(C(=O)NCCCOC(=O)C=C)c6)cc5)=C4C(=O)N3)cc2)cc(C(=O)NCCCCN(CC)CC)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38
HDAC4 P56524 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
MCHR1 Q99705 6/20 0.37
TDP1 Q9NUW8 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
PAX8 Q06710 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786333 0.87 HDAC4 (0.48) POLBDRD2DRD4DRD3HDAC4
SCHEMBL21657766 0.83 RXFP1 (0.44) POLBHDAC4HDAC2HDAC8HDAC6
SCHEMBL23306815 0.82 TDP1 (0.45) POLBDRD2DRD4DRD3HDAC4
SCHEMBL23306823 0.81 GRIN1 (0.44) POLBDRD2DRD4DRD3MCHR1
SCHEMBL24942175 0.77 HDAC3 (0.47) POLBHDAC4HDAC2HDAC8HDAC6
SCHEMBL21657765 0.76 MAPT (0.42) POLBHDAC4HDAC2HDAC8HDAC6
SCHEMBL21657763 0.75 RXFP1 (0.36) POLBHDAC4HDAC2HDAC8HDAC6
SCHEMBL12577581 0.74 DRD2 (0.58) DRD2DRD4DRD3HDAC4HDAC2
SCHEMBL13078928 0.70 POLB (0.56) POLBHDAC4HDAC2HDAC8HDAC6
SCHEMBL23904108 0.70 TDP1 (0.64) POLBDRD2DRD4DRD3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518827-B2 Curable composition, method for producing curable composition, film, color filter, method for manufacturing color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210122850-A1 CURABLE COMPOSITION, METHOD FOR PRODUCING CURABLE COMPOSITION, FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-04-29 US disclosed
WO-2020022247-A1 CURABLE COMPOSITION, PRODUCTION METHOD FOR CURABLE COMPOSITION, FILM, COLOR FILTER, PRODUCTION METHOD FOR COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE 富士フイルム株式会社 2020-01-30 WO disclosed