Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378017 | 1.00 | MMP9 (0.31) | MMP9 | |
| SCHEMBL28562380 | 0.77 | MMP9 (0.33) | MMP9 | |
| SCHEMBL21659003 | 0.77 | MMP9 (0.33) | MMP9 | |
| SCHEMBL14378068 | 0.69 | TSHR (0.34) | MMP9 | |
| Hydrochloric Acid SCHEMBL28905053 | 0.69 | CYP19A1 (0.44) | MMP9 | |
| SCHEMBL16361929 | 0.69 | — | — | |
| SCHEMBL14554812 | 0.68 | MMP9 (0.33) | MMP9 | |
| SCHEMBL22450108 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL14378053 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL14378098 | 0.67 | GRIN1 (0.34) | MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12486280-B2 | CDK inhibitors and uses thereof | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2025-12-02 | — | — | US | disclosed |
| EP-3830082-B1 | CDK INHIBITORS AND USES THEREOF | CALIFORNIA INST OF TECHN (US) | 2025-02-26 | — | — | EP | disclosed |
| US-20220106325-A1 | CDK INHIBITORS AND USES THEREOF | 1200 PHARMA LLC | 2022-04-07 | — | — | US | disclosed |
| CN-112703186-A | CDK inhibitors and uses thereof | 加利福尼亚技术学院 | 2021-04-23 | — | — | CN | disclosed |
| WO-2020023917-A1 | CDK INHIBITORS AND USES THEREOF | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106325-A1 | CDK INHIBITORS AND USES THEREOF | CDK6, CDK4, CDK3 | MMP9 1707/4885 |
| US-12486280-B2 | CDK inhibitors and uses thereof | CDK6, CDK4, CDK3 | MMP9 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.