Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22007658 | 0.88 | — | — | |
| SCHEMBL22450108 | 0.82 | KDM4E (0.32) | KDM4ELMNAPOLB | |
| SCHEMBL14554860 | 0.71 | POLB (0.33) | POLB | |
| SCHEMBL14378065 | 0.70 | — | — | |
| SCHEMBL14378057 | 0.69 | POLB (0.32) | POLB | |
| SCHEMBL14378059 | 0.68 | — | — | |
| SCHEMBL14378025 | 0.68 | POLB (0.33) | POLB | |
| SCHEMBL21658740 | 0.67 | MMP9 (0.31) | — | |
| SCHEMBL14378017 | 0.67 | MMP9 (0.31) | — | |
| SCHEMBL14554849 | 0.65 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210155592-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-05-27 | — | — | US | disclosed |
| EP-3712140-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | California Institute of Technology (US) | 2020-09-23 | — | — | EP | disclosed |
| US-10343996-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-09 | — | — | US | disclosed |
| US-10035769-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-07-31 | — | — | US | disclosed |
| US-10035769-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-07-31 | — | — | US | disclosed |
| US-20170137382-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-18 | — | — | US | disclosed |
| US-20170137382-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-18 | — | — | US | disclosed |
| US-8822679-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-02 | — | — | US | disclosed |
| US-8822679-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130267699-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-10 | — | — | US | disclosed |
| US-20130267699-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-10 | — | — | US | disclosed |
| US-20130012701-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-01-10 | — | — | US | disclosed |
| US-20130012701-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2013-01-10 | — | — | US | disclosed |
| WO-2012178129-A2 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267699-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | TSHR 4188/4885KDM4E 650/4885LMNA 2321/4885 |
| US-20210155592-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | TSHR 4188/4885KDM4E 650/4885LMNA 2321/4885 |
| US-10343996-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | TSHR 4188/4885KDM4E 650/4885LMNA 2321/4885 |
| US-10035769-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | TSHR 4188/4885KDM4E 650/4885LMNA 2321/4885 |
| US-20130012701-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | PRMT9, AFF1, PRMT1 | TSHR 1822/4885KDM4E 304/4885LMNA 2955/4885 |
| US-20170137382-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | TSHR 4188/4885KDM4E 650/4885LMNA 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.