Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378053 | 0.82 | TSHR (0.31) | KDM4ELMNAPOLB | |
| SCHEMBL22007658 | 0.72 | — | — | |
| SCHEMBL17345852 | 0.70 | LMNA (0.37) | LMNA | |
| SCHEMBL29109490 | 0.68 | KMT2A (0.32) | POLB | |
| SCHEMBL21658740 | 0.68 | MMP9 (0.31) | — | |
| SCHEMBL22449987 | 0.68 | GRIN1 (0.35) | POLB | |
| SCHEMBL22450093 | 0.68 | GRIN1 (0.35) | POLB | |
| SCHEMBL14378017 | 0.68 | MMP9 (0.31) | — | |
| SCHEMBL13003396 | 0.65 | — | — | |
| SCHEMBL11659434 | 0.64 | GAA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712140-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | California Institute of Technology (US) | 2020-09-23 | — | — | EP | disclosed |