SCHEMBL2166294

SCHEMBL2166294

O=C(O)c1ccc2c(C(=O)O)c1-c1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
MAPT P10636 5/20 0.53
LMNA P02545 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
POLB P06746 2/20 0.47
MAPK1 P28482 2/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
WDR5 P61964 1/20 0.47
ALOX15 P16050 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
GFER P55789 1/20 0.46
HNF4A P41235 1/20 0.46
MYC P01106 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MMP14 P50281 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10784745 0.88 MYC (0.55) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL87698 0.86 MAPT (0.52) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL1652930 0.84 ALDH1A1 (0.57) ALDH1A1MAPTLMNAL3MBTL1MEN1
Hydrochloric Acid SCHEMBL4002701 0.84 MAPT (0.50) ALDH1A1MAPTLMNAL3MBTL1MEN1
Hydrochloric Acid SCHEMBL11418766 0.84 MAPT (0.50) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL11223890 0.83 ACMSD (0.47) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL7081861 0.83 ALDH1A1 (0.50) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL995362 0.80 HNF4A (0.52) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL11770044 0.79 MAPT (0.39) ALDH1A1MAPTLMNAL3MBTL1MEN1
SCHEMBL5345063 0.79 ALDH1A1 (0.39) ALDH1A1MAPTLMNAL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7985828-B2 Solid polymer electrolyte, method for manufacturing the same and use thereof NATIONAL SUN YAT-SEN UNIVERSITY (TW) 2011-07-26 US disclosed
EP-0868556-A2 FIBROUS-FORMATION AEROGEL COMPOSITE MATERIAL CONTAINING AT LEAST ONE THERMOPLASTIC FIBROUS MATERIAL, PROCESS FOR THE PRODUCTION THEREOF, AND USE THEROF Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-10-07 EP disclosed
WO-1997023675-A2 FIBROUS-FORMATION AEROGEL COMPOSITE MATERIAL CONTAINING AT LEAST ONE THERMOPLASTIC FIBROUS MATERIAL, PROCESS FOR THE PRODUCTION THEREOF, AND USE THEROF HOECHST RESEARACH & TECHNOLOGY (DE) 1997-07-03 WO disclosed
US-5393848-A Mixing preformed thermotropic liquid crystalline polymer with reactants necessary to form second liquid crystalline polymer, heating above melting point to form uniform blend HOECHST CELANESE CORP. (US) 1995-02-28 US disclosed
WO-1993004127-A1 PROCESS FOR FORMING IMPROVED LIQUID CRYSTALLINE POLYMER BLENDS HOECHST CELANESE CORPORATION (US) 1993-03-04 WO disclosed
WO-1991010707-A1 IMPROVED PROCESS FOR FORMING POLY[CO(4-OXYBENZOATE/PARAPHENYLENEISOPHTHALATE)] AND RESULTING PRODUCT HOECHST CELANESE CORPORATION (US) 1991-07-25 WO disclosed