Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542942 | 0.79 | LMNA (0.40) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL297268 | 0.77 | — | — | |
| SCHEMBL4578526 | 0.75 | EPHX2 (0.53) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23513804 | 0.74 | KDM4E (0.41) | ALDH1A1TDP1 | |
| SCHEMBL11165110 | 0.74 | TSHR (0.44) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL605190 | 0.73 | — | — | |
| SCHEMBL18619439 | 0.73 | ALDH1A1 (0.48) | CNR1ALDH1A1NAAACNR2FAAH | |
| SCHEMBL12642638 | 0.73 | CASP2 (0.47) | ALDH1A1NAAAFAAHMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6415392 | 0.72 | KDM4E (0.41) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL2320293 | 0.72 | ALDH1A1 (0.57) | CNR1ALDH1A1NAAACNR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604533-A1 | SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS | Arbutus Biopharma Corporation (CA) | 2020-02-05 | — | — | EP | disclosed |