SCHEMBL2166364

SCHEMBL2166364

CC(=O)c1cc(Cl)c2ccccc2c1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.71
KMT2A Q03164 4/20 0.71
MAPT P10636 4/20 0.71
MEN1 O00255 3/20 0.71
HSD17B10 Q99714 3/20 0.71
HPGD P15428 2/20 0.71
HTT P42858 2/20 0.71
ALDH1A1 P00352 1/20 0.71
PKM P14618 1/20 0.71
MCL1 Q07820 3/20 0.68
NSD2 O96028 1/20 0.68
POLB P06746 1/20 0.68
TNF P01375 1/20 0.47
NOD1 Q9Y239 1/20 0.47
CYP2C9 P11712 2/20 0.46
THRB P10828 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
ATIC P31939 1/20 0.46
HMGB1 P09429 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485443 0.83 HSD17B10 (1.00) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL14432590 0.83 KDM4E (0.73) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL29904678 0.81 MAPT (1.00) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL10902143 0.81 MAPT (1.00) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL31300298 0.81 KDM4E (0.65) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL13401400 0.81 KDM4E (0.65) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL9658721 0.81 ALDH1A1 (0.65) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL27707703 0.79 MAPT (0.70) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL13656899 0.78 MEN1 (0.66) KDM4EKMT2AMAPTMEN1HSD17B10
SCHEMBL6622354 0.78 MAPT (0.68) KDM4EKMT2AMAPTMEN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415304-B Method for producing iron complex and method for producing ester compound using iron complex 株式会社可乐丽 2022-07-22 CN disclosed
EP-3476828-B1 METHOD FOR PRODUCING IRON COMPLEXES AND METHOD FOR PRODUCING ESTER COMPOUNDS USING IRON COMPLEX KURARAY CO (JP) 2021-03-17 EP disclosed
US-10646859-B2 Method for producing iron complexes and method for producing ester compounds using iron complex KURARAY CO., LTD. (JP) 2020-05-12 US disclosed
US-20190351401-A1 METHOD FOR PRODUCING IRON COMPLEXES AND METHOD FOR PRODUCING ESTER COMPOUNDS USING IRON COMPLEX KURARAY CO., LTD (JP) 2019-11-21 US disclosed
EP-3476828-A1 METHOD FOR PRODUCING IRON COMPLEX AND METHOD FOR PRODUCING ESTER COMPOUND USING IRON COMPLEX Kuraray Co., Ltd. (JP) 2019-05-01 EP disclosed
US-8680108-B2 Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors INCYTE CORPORATION (US) 2014-03-25 US disclosed
US-8680108-B2 Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors INCYTE CORPORATION (US) 2014-03-25 US disclosed
US-8680108-B2 Substituted fused aryl and heteroaryl derivatives as PI3K inhibitors INCYTE CORPORATION (US) 2014-03-25 US disclosed
US-20110183985-A1 SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS INCYTE CORPORATION 2011-07-28 US disclosed
US-20110183985-A1 SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS INCYTE CORPORATION 2011-07-28 US disclosed
EP-0362771-A1 Photochromic substances Optische Werke G. Rodenstock (DE) 1990-04-11 EP disclosed
WO-1990003379-A1 PHOTOCHROMIC SUBSTANCES OPTISCHE WERKE G. RODENSTOCK (DE) 1990-04-05 WO disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4826977-A Photochromic spiropyran compounds THE PLESSEY COMPANY PLC (GB) 1989-05-02 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-87104184-A PHOTOCHROMIC SPIROPYRAN COMPOUNDS 1988-06-29 CN disclosed
EP-0246114-A2 Photochromic spiropyran compounds GEC-MARCONI LIMITED (GB) 1987-11-19 EP disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190351401-A1 METHOD FOR PRODUCING IRON COMPLEXES AND METHOD FOR PRODUCING ESTER COMPOUNDS USING IRON COMPLEX FECH, FTH1, TFRC KDM4E 1419/4885KMT2A 1773/4885MAPT 4198/4885
US-20110183985-A1 SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS PIK3R1, PIK3R3, PIK3R2 KDM4E 1058/4885KMT2A 1147/4885MAPT 4496/4885
US-10646859-B2 Method for producing iron complexes and method for producing ester compounds using iron complex FECH, FTH1, TFRC KDM4E 1419/4885KMT2A 1773/4885MAPT 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.