Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7930572 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| Fluoride Ion SCHEMBL1130885 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL4577365 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| Iodide SCHEMBL7931400 | 0.97 | NPC1 (0.40) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL2861801 | 0.88 | NPC1 (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL8416214 | 0.88 | NPC1 (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7611881 | 0.88 | NPC1 (0.37) | NPC1RAB9APNMTHTR7HTR2B | |
| Syringol SCHEMBL7930372 | 0.87 | RAB9A (0.34) | NPC1RAB9ADRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL820139 | 0.86 | NPC1 (0.35) | NPC1RAB9APNMTHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL218253 | 0.86 | NPC1 (0.35) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225707-A1 | Articles Formed From Polypropylene Prepared with a Single-Site Catalyst and Poly(hydroxyl carboxylic acid) Blends | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-08-29 | — | — | US | claimed |
| US-8445595-B2 | Polypropylene prepared with a single-site catalyst and poly(hydroxyl carboxylic acid) blends | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-05-21 | — | — | US | claimed |
| EP-2160233-B1 | PROCESS FOR THE POLYMERISATION OF OLEFINS | TOTAL RES & TECHNOLOGY FELUY (BE) | 2012-10-17 | — | — | EP | claimed |
| US-20100234544-A1 | Process for the Polymerisation of Olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-09-16 | — | — | US | claimed |
| US-7662895-B2 | comprising polypropylene which is produced in presence of a metallocene transition metal catalyst and an activator; peak melting point temperature below about 110 degrees C., a tensile set of 40% or less, and greater than or equal to about 60% [r]dyads | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-02-16 | — | — | US | claimed |
| EP-2006012-A1 | Process for the polymerisation of olefins | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-12-24 | — | — | EP | claimed |
| US-20070117941-A1 | Syndiotactic propylene elastomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-24 | — | — | US | claimed |
| EP-0572990-B2 | Method for preparing ethylene copolymer | MITSUI TOATSU CHEMICALS (JP) | 2000-08-16 | — | — | EP | claimed |
| US-5652315-A | Method for preparing ethylene copolymer | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-07-29 | — | — | US | claimed |
| EP-0572990-A2 | Method for preparing ethylene copolymer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-08 | — | — | EP | claimed |
| JP-4327211-A | — | — | None | — | — | JP | disclosed |
| EP-3237461-B1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2026-03-18 | — | — | EP | disclosed |
| CN-119371579-A | Metallocene catalyst system, polyisobutene and preparation method thereof | 中国石油天然气集团有限公司 | 2025-01-28 | — | — | CN | disclosed |
| WO-2024185503-A1 | RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME | 東ソー株式会社 | 2024-09-12 | — | — | WO | disclosed |
| US-20230174758-A1 | POLYPROPYLENE-BASED RESIN COMPOSITION, LAMINATE, AND METHODS FOR PRODUCING THEM | JAPAN POLYPROPYLENE CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| EP-0512741-A1 | Process for producing a propylene random copolymer | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-11-11 | — | — | EP | disclosed |
| EP-0511846-A1 | Aminated olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-11-04 | — | — | EP | disclosed |
| EP-0511665-A2 | Catalyst for polymerizing an olefin and method for producing an olefin polymer | Mitsubishi Chemical Corporation (JP) | 1992-11-04 | — | — | EP | disclosed |
| EP-0498675-A2 | Production of alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0487278-A2 | Functionalized olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-27 | — | — | EP | disclosed |