Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL216652 | 0.88 | NPC1 (0.40) | NPC1RAB9AHTR7HTR2BPNMT | |
| Fluoride Ion SCHEMBL1130885 | 0.86 | NPC1 (0.40) | NPC1RAB9AHTR7HTR2BPNMT | |
| SCHEMBL4577365 | 0.86 | NPC1 (0.40) | NPC1RAB9AHTR7HTR2BPNMT | |
| Bromide SCHEMBL7930572 | 0.86 | NPC1 (0.40) | NPC1RAB9AHTR7HTR2BPNMT | |
| Iodide SCHEMBL7931400 | 0.86 | NPC1 (0.40) | NPC1RAB9AHTR7HTR2BPNMT | |
| Hydrochloric Acid SCHEMBL5080554 | 0.86 | PNMT (0.30) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL5081135 | 0.86 | PNMT (0.30) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL5079587 | 0.86 | PNMT (0.30) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL811765 | 0.85 | PNMT (0.30) | PNMT | |
| Hydrochloric Acid SCHEMBL2856383 | 0.82 | KMT2A (0.34) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661921-B1 | Synthetic lubricating oil and lubricating oil composition thereof | MITSUI CHEMICALS INC (JP) | 2019-07-17 | — | — | EP | disclosed |
| US-7795194-B2 | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS, INC. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| EP-1661921-A1 | Synthetic lubricating oil and lubricating oil composition thereof | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |