Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138789 | 1.00 | LPL (0.38) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL19747926 | 0.87 | LPL (0.36) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL28033296 | 0.87 | LPL (0.36) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL252452 | 0.87 | LPL (0.38) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL15031655 | 0.83 | LPL (0.34) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL24456587 | 0.80 | LPL (0.34) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL29652819 | 0.80 | LPL (0.34) | LPLLIPGESR2JAK2BTK | |
| SCHEMBL15010917 | 0.80 | EGFR (0.36) | LPLLIPGESR2AAK1 | |
| SCHEMBL29695359 | 0.80 | EGFR (0.36) | LPLLIPGESR2AAK1 | |
| SCHEMBL21042445 | 0.79 | LIPG (0.50) | LPLLIPGJAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023393-A1 | KINASE ANTAGONISTS AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS, INC. (US) | 2020-01-30 | — | — | WO | disclosed |